Synthesis and Evaluation of Small Molecule Drug Conjugates Harnessing Thioester-Linked Maytansinoids
Ligand-targeting drug conjugates are a class of clinically validated biopharmaceutical drugs constructed by conjugating cytotoxic drugs with specific disease antigen targeting ligands through appropriate linkers. The integrated linker-drug motif embedded within such a system can prevent the prematur...
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Main Authors: | Chen-Fu Lo (Author), Tai-Yu Chiu (Author), Yu-Tzu Liu (Author), Li-Rung Huang (Author), Teng-Kuang Yeh (Author), Kuan-Hsun Huang (Author), Kuan-Liang Liu (Author), Chia-Yu Hsu (Author), Ming-Yu Fang (Author), Yu-Chen Huang (Author), Tsu-An Hsu (Author), Chiung-Tong Chen (Author), Lun Kelvin Tsou (Author) |
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Format: | Book |
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MDPI AG,
2022-06-01T00:00:00Z.
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