Formulation, Preparation, Characterization, and Evaluation of Dicarboxylic Ionic Liquid Donepezil Transdermal Patches

• Autori principali: Linh Dinh (Autore), Soohun Lee (Autore), Sharif Md Abuzar (Autore), Heejun Park (Autore), Sung-Joo Hwang (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2022-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Donepezil (DPZ) is generally administered orally to treat Alzheimer's disease (AD). However, oral administration can cause gastrointestinal side effects. Therefore, to enhance compliance, a new way to deliver DPZ from transdermal patch was developed. Ionic bonds were created by dissolving dicar...