Novel glucokinase activators: A structure-based pharmacophore modeling, QSAR analysis, and molecular dynamics approach
Glucokinase (GK) activators are promising candidates for type 2 diabetes treatment. This study utilized structure-based pharmacophore modeling and QSAR analysis to identify novel activators. Virtual screening of a 250,000-compound library yielded eight new candidates with significant in vitro activi...
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| Main Authors: | , , |
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| Format: | Book |
| Published: |
Pensoft Publishers,
2024-08-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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Internet
Connect to this object online.3rd Floor Main Library
| Call Number: |
A1234.567 |
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| Copy 1 | Available |