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Novel glucokinase activators: A structure-based pharmacophore modeling, QSAR analysis, and molecular dynamics approach

Glucokinase (GK) activators are promising candidates for type 2 diabetes treatment. This study utilized structure-based pharmacophore modeling and QSAR analysis to identify novel activators. Virtual screening of a 250,000-compound library yielded eight new candidates with significant in vitro activi...

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Bibliografske podrobnosti
Main Authors:	Mansour Al-Sayed Ahmad (Author), Belal O. Al-Najjar (Author), Ashok Shakya (Author)
Format:	Knjiga
Izdano:	Pensoft Publishers, 2024-08-01T00:00:00Z.
Teme:	article
Online dostop:	Connect to this object online.
Oznake:	Označite Brez oznak, prvi označite!

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