Alteration in Metabolism and Toxicity of Acetaminophen Upon Repeated Administration in Rats

Our previous studies showed that administration of a subtoxic dose of acetaminophen (APAP) to female rats increased generation of carbon monoxide from dichloromethane, a metabolic reaction catalyzed mainly by cytochrome P450 (CYP) 2E1. In this study we examined the changes in metabolism and toxicity...

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Main Authors: Sun J. Kim (Author), Min Y. Lee (Author), Do Y. Kwon (Author), Sung Y. Kim (Author), Young C. Kim (Author)
Format: Book
Published: Elsevier, 2009-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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