Dosing recommendation of nirmatrelvir/ritonavir using an integrated population pharmacokinetic analysis

• Main Authors: Phylinda L. S. Chan (Author), Ravi Shankar P. Singh (Author), Donna S. Cox (Author), Haihong Shi (Author), Bharat Damle (Author), Timothy Nicholas (Author)
• Format: Book
• Published: Wiley, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Protease inhibitor nirmatrelvir coadministered with ritonavir as a pharmacokinetic enhancer (PAXLOVID™; Pfizer Inc) became the first orally bioavailable antiviral agent granted Emergency Use Authorization in the United States in patients ≥12 years old with mild to moderate coronavirus disea...