Discovery of potential WEE1 inhibitors via hybrid virtual screening

G2/M cell cycle checkpoint protein WEE1 kinase is a promising target for inhibiting tumor growth. Although various WEE1 inhibitors have entered clinical investigations, their therapeutic efficacy and safety profile remain unsatisfactory. In this study, we employed a comprehensive virtual screening w...

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Main Authors: Tingting Jin (Author), Wei Xu (Author), Roufen Chen (Author), Liteng Shen (Author), Jian Gao (Author), Lei Xu (Author), Xinglong Chi (Author), Nengming Lin (Author), Lixin Zhou (Author), Zheyuan Shen (Author), Bo Zhang (Author)
Format: Book
Published: Frontiers Media S.A., 2023-12-01T00:00:00Z.
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