Tryptophan Metabolism in Bipolar Disorder in a Longitudinal Setting

• Main Authors: Frederike T. Fellendorf (Author), Johanna M. Gostner (Author), Melanie Lenger (Author), Martina Platzer (Author), Armin Birner (Author), Alexander Maget (Author), Robert Queissner (Author), Adelina Tmava-Berisha (Author), Cornelia A. Pater (Author), Michaela Ratzenhofer (Author), Jolana Wagner-Skacel (Author), Susanne A. Bengesser (Author), Nina Dalkner (Author), Dietmar Fuchs (Author), Eva Z. Reininghaus (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Immune-mediated inflammatory processes and oxidative stress are involved in the aetiopathogenesis of bipolar disorder (BD) and weight-associated comorbidities. Tryptophan breakdown via indoleamine 2,3-dioxygenase-1 (IDO-1) along the kynurenine axis concomitant with a pro-inflammatory state was found...