ALK expressed in a gastrointestinal stromal tumor harboring PDGFRA p. D842V mutation:a case report

• Main Authors: Jun Fan (Author), Ming Yang (Author), Bo Huang (Author), Zhenkao Wang (Author), Danju Luo (Author), Jiwei Zhang (Author), Peng Zhang (Author), Heshui Shi (Author), Yan Li (Author), Xiu Nie (Author)
• Format: Book
• Published: BMC, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Gastrointestinal stromal tumors (GISTs) are the most common type of adult mesenchymal neoplasms. The events that drive GIST oncogenesis are primarily KIT or PDGFRA mutations, which lead to the susceptibility of these tumors to small-molecule tyrosine kinase inhibitors such as ima...