Allele-specific recombinase polymerase amplification for real-time detection of sickle cell anaemia in low-resource settings: evaluation of an isothermal nucleic acid amplification test to detect the βS globin point mutation in paediatric patients

Background: Sickle cell anaemia is a common, life-threatening disorder caused by a point mutation in the β globin gene. The high cost and complexity of conventional diagnostic methods limit the scope and sustainability of newborn screening for sickle cell anaemia and other haemoglobin disorders in r...

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Main Authors: Mary Natoli, PhD (Author), Megan Chang, BA (Author), Kathryn Kundrod, PhD (Author), Jackson Coole, BS (Author), Gladstone Airewele, MD (Author), Venée N Tubman, MD (Author), Rebecca Richards-Kortum, PhD (Author)
Format: Book
Published: Elsevier, 2021-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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