Reduction in C-Peptide Levels and Influence on Pharmacokinetics and Pharmacodynamics of Insulin Preparations: How to Conduct a High-Quality Euglycemic Clamp Study

Objective: The aim of the study was to investigate the different extent of inhibition of endogenous insulin secretion by the reduction of C-peptide levels in an euglycemic clamp study and its effects on the evaluation of pharmacokinetics, pharmacodynamics of insulin preparations, and quality of clam...

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Main Authors: Yi Tao (Author), Mingxue Zhu (Author), Junliang Pu (Author), Peilin Zhang (Author), Lei Wan (Author), Chengyong Tang (Author)
Format: Book
Published: Frontiers Media S.A., 2021-12-01T00:00:00Z.
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