Renoprotection of Microcystin-RR in Unilateral Ureteral Obstruction-Induced Renal Fibrosis: Targeting the PKM2-HIF-1α Pathway

• Main Authors: Yan Ren (Author), Jie Wang (Author), Wenwen Guo (Author), Jingwen Chen (Author), Xin Wu (Author), Shubo Gu (Author), Lizhi Xu (Author), Zhiwei Wu (Author), Yaping Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Renal fibrosis is a pathological characteristic of the endpoint of chronic kidney disease (CKD), which remains a major public health problem. None of the current therapies is effective in stopping kidney fibrosis progression. In light of our novel detection of a potential antifibrosis of microcystin...