Impact of Drug-Mediated Inhibition of Intestinal Transporters on Nutrient and Endogenous Substrate Disposition...an Afterthought?

A large percentage (~60%) of prescription drugs and new molecular entities are designed for oral delivery, which requires passage through a semi-impervious membrane bilayer in the gastrointestinal wall. Passage through this bilayer can be dependent on membrane transporters that regulate the absorpti...

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Main Authors: Kshitee Kharve (Author), Andrew S. Engley (Author), Mary F. Paine (Author), Jason A. Sprowl (Author)
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Publicado em: MDPI AG, 2024-03-01T00:00:00Z.
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3rd Floor Main Library

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