Anti-Inflammatory Effects of the LK5 Herbal Complex on LPS- and IL-4/IL-13-Stimulated HaCaT Cells and a DNCB-Induced Animal Model of Atopic Dermatitis in BALB/c Mice

• Main Authors: Hyun-Jeong Kim (Author), So-Yeon Kim (Author), Ho Jung Bae (Author), Yu-Yeong Choi (Author), Ju-Yeon An (Author), Ye Eun Cho (Author), So-Young Cho (Author), Su-Jung Lee (Author), Sanghyun Lee (Author), MinSub Sin (Author), Young Min Yun (Author), Jong Ryul Lee (Author), Se Jin Park (Author)
• Format: Book
• Published: MDPI AG, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Atopic dermatitis (AD) is a chronic inflammatory skin disease influenced by a complex interplay of genetic and environmental factors. The activation of the JAK-STAT pathway increases the expression of inflammatory cytokines such as IL-4 and IL-13, further deteriorating AD. Therefore, for the treatme...