Discovery of novel isonipecotic acid-based heteroaryl amino acid derivatives as potential anticonvulsant agents: Design, synthesis, in-silico ADME study, and molecular docking studies

• Autores principales: Mohammad M Ahmad (Autor), Naseem Akhtar (Autor), Shamshir Khan (Autor), Mohd Rashid (Autor), Md Tanwir Athar (Autor), Zabih Ullah (Autor), Mohamad Taleuzzaman (Autor)
• Formato: Libro
• Publicado: Wolters Kluwer Medknow Publications, 2023-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Background: Epilepsy is a neurological disorder characterized by anomalous brain activity, convulsions, and odd behavior. Several substituted-(naphthalen-2-yl)-3-(1H-indol-3-yl) allyl)-1,4-dihydropyridine-4-carboxylic acid derivatives (5a-j) were intended to be produced in the current research effor...