The changes of hepatic bile acid synthesis and transport and bile acids profiles in isopsoralen-induced liver injury C57BL/6J mice

• Main Authors: Wei-jie Men (Author), Zhao-jun Meng (Author), Qin Wang (Author), Meng-ying Chen (Author), Yu-xia Zhai (Author), Hong Shi (Author), An-hong Wang (Author), Kun Zhou (Author)
• פורמט: ספר
• יצא לאור: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Contest Isopsoralen, one of the main active and quality-control compounds in Psoralea corylifolia L. (Fabaceae), has antitumor and oestrogen-like effects. Previous studies demonstrated that isopsoralen induced hepatotoxicity and its long-term exposure led to cholestatic liver injury.Objective This s...