Farnesoid-X receptor as a therapeutic target for inflammatory bowel disease and colorectal cancer

• Main Authors: Mengjiao Zhou (Author), Danfeng Wang (Author), Xiang Li (Author), Ying Cao (Author), Chengxue Yi (Author), Dickson Kofi Wiredu Ocansey (Author), Yuling Zhou (Author), Fei Mao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Farnesoid-X receptor (FXR), as a nuclear receptor activated by bile acids, is a vital molecule involved in bile acid metabolism. Due to its expression in immune cells, FXR has a significant effect on the function of immune cells and the release of chemokines when immune cells sense changes in bile a...