Thymoquinone inhibited vasculogenic capacity and promoted mesenchymal-epithelial transition of human breast cancer stem cells

• Main Authors: Sanya Haiaty (Author), Mohammad-Reza Rashidi (Author), Maryam Akbarzadeh (Author), Ahad Bazmany (Author), Mostafa Mostafazadeh (Author), Saba Nikanfar (Author), Zohre Zibaei (Author), Reza Rahbarghazi (Author), Mohammad Nouri (Author)
• Format: Book
• Published: BMC, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Vasculogenic mimicry (VM) is characterized by the formation of tubular structure inside the tumor stroma. It has been shown that a small fraction of cancer cells, namely cancer stem cells (CSCs), could stimulate the development of vascular units in the tumor niche, leading to enh...