Hapln1 promotes dedifferentiation and proliferation of iPSC-derived cardiomyocytes by promoting versican-based GDF11 trapping

• Автори: Ding-Jun Hao (Автор), Yue Qin (Автор), Shi-Jie Zhou (Автор), Bu-Huai Dong (Автор), Jun-Song Yang (Автор), Peng Zou (Автор), Li-Ping Wang (Автор), Yuan-Ting Zhao (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2024-03-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Hyaluronan and proteoglycan link protein 1 (Hapln1) supports active cardiomyogenesis in zebrafish hearts, but its regulation in mammal cardiomyocytes is unclear. This study aimed to explore the potential regulation of Hapln1 in the dedifferentiation and proliferation of cardiomyocytes and its therap...