Hydrogel-Assisted Antisense LNA Gapmer Delivery for In Situ Gene Silencing in Spinal Cord Injury

Hydrogel-Assisted Antisense LNA Gapmer Delivery for In Situ Gene Silencing in Spinal Cord Injury

After spinal cord injury (SCI), nerve regeneration is severely hampered due to the establishment of a highly inhibitory microenvironment at the injury site, through the contribution of multiple factors. The potential of antisense oligonucleotides (AONs) to modify gene expression at different levels,...

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Main Authors: Pedro M.D. Moreno (Author), Ana R. Ferreira (Author), Daniela Salvador (Author), Maria T. Rodrigues (Author), Marília Torrado (Author), Eva D. Carvalho (Author), Ulf Tedebark (Author), Mónica M. Sousa (Author), Isabel F. Amaral (Author), Jesper Wengel (Author), Ana P. Pêgo (Author)
Format: Book
Published: Elsevier, 2018-06-01T00:00:00Z.
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3rd Floor Main Library

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