Functional differences in the mu opioid receptor SNP 118A>G are dependent on receptor splice‐variant and agonist‐specific recruitment of β‐arrestin
Abstract The OPRM1 gene codes for the mu opioid receptor (MOR) and polymorphisms are associated with complex patient clinical responses. The most studied single nucleotide polymorphism (SNP) in OPRM1 is adenine (A) substituted by guanine (G) at position 118 (118A>G, rs1799971) leading to a substi...
Saved in:
Main Authors: | Casey Patrick (Author), Utibeabasi Ettah (Author), Vu Nguyen (Author), Caitlin Hart (Author), Evan Atchley (Author), Krishna Mallela (Author), Robert I. Scheinman (Author), Andrew A. Monte (Author) |
---|---|
Format: | Book |
Published: |
Wiley,
2024-08-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The Effect of Cell Surface Expression and Linker Sequence on the Recruitment of Arrestin to the GIP Receptor
by: Suleiman Al-Sabah, et al.
Published: (2020) -
Analgesic tone conferred by constitutively active mu opioid receptors in mice lacking β-arrestin 2
by: Hales Tim G, et al.
Published: (2011) -
A novel alternatively spliced isoform of the mu-opioid receptor: functional antagonism
by: Wentworth Sean, et al.
Published: (2010) -
Dopamine-induced arrestin recruitment and desensitization of the dopamine D4 receptor is regulated by G protein-coupled receptor kinase-2
by: Viktor Burström, et al.
Published: (2023) -
Investigation of adenosine A1 receptor-mediated β-arrestin 2 recruitment using a split-luciferase assay
by: Luisa Saecker, et al.
Published: (2023)