Sphingosine-1-Phosphate Receptors Modulators Decrease Signs of Neuroinflammation and Prevent Parkinson's Disease Symptoms in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model

Sphingosine-1-phosphate (S1P) is a potent bioactive lipid mediator that acts as a natural ligand upon binding to five different receptors that are located in astrocytes, oligodendrocytes, microglial and neuronal cells. Recently, global activation of these receptors by FTY720 (fingolimod) has been su...

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Main Authors: Élise Pépin (Author), Tim Jalinier (Author), Guillaume L. Lemieux (Author), Guy Massicotte (Author), Michel Cyr (Author)
Format: Book
Published: Frontiers Media S.A., 2020-02-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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