Activation inhibitors of nuclear factor kappa B protect neurons against the NMDA-induced damage in the rat retina

• Päätekijät: Kenji Sakamoto (Tekijä), Tatsuya Okuwaki (Tekijä), Hiroko Ushikubo (Tekijä), Asami Mori (Tekijä), Tsutomu Nakahara (Tekijä), Kunio Ishii (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Elsevier, 2017-10-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

We reported that high-mobility group Box-1 (HMGB1) was involved in excitoneurotoxicity in the retina. HMGB1 is known to activate nuclear factor kappa B (NF-κB). However, the role of NF-κB in excitotoxicity is still controversial. Here, we demonstrated that NF-κB activation induced by NMDA led to...