Standardised imaging pipeline for phenotyping mouse laterality defects and associated heart malformations, at multiple scales and multiple stages

Laterality defects are developmental disorders resulting from aberrant left/right patterning. In the most severe cases, such as in heterotaxy, they are associated with complex malformations of the heart. Advances in understanding the underlying physiopathological mechanisms have been hindered by the...

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Main Authors: Audrey Desgrange (Author), Johanna Lokmer (Author), Carmen Marchiol (Author), Lucile Houyel (Author), Sigolène M. Meilhac (Author)
Format: Book
Published: The Company of Biologists, 2019-07-01T00:00:00Z.
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