Screening of a Small Molecule Compound Library Identifies Toosendanin as an Inhibitor Against Bunyavirus and SARS-CoV-2

• Главные авторы: Shufen Li (Автор), Meidi Ye (Автор), Yuanqiao Chen (Автор), Yulan Zhang (Автор), Jiachen Li (Автор), Wei Liu (Автор), Hao Li (Автор), Ke Peng (Автор)
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• Опубликовано: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Предметы: article
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Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne virus causing serious infectious disease with a high case-fatality of up to 50% in severe cases. Currently, no effective drug has been approved for the treatment of SFTSV infection. Here, we performed a high-throughp...