Screening of a Small Molecule Compound Library Identifies Toosendanin as an Inhibitor Against Bunyavirus and SARS-CoV-2

• Autores principales: Shufen Li (Autor), Meidi Ye (Autor), Yuanqiao Chen (Autor), Yulan Zhang (Autor), Jiachen Li (Autor), Wei Liu (Autor), Hao Li (Autor), Ke Peng (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne virus causing serious infectious disease with a high case-fatality of up to 50% in severe cases. Currently, no effective drug has been approved for the treatment of SFTSV infection. Here, we performed a high-throughp...