Preparation and evaluation of microspheres with dual polymeric film to minimize burst effect of highly water soluble drug

• Main Authors: Liaqat Ali (Author), Mahmood Ahmad (Author), Usman Minhas (Author), Jawad Ahmad Khan (Author), Muhammad Yousuf (Author), Muhammad Sohail (Author), Khaleeq Anwer (Author)
• Format: Book
• Published: AMMANIF, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Double-layered controlled release microspheres of venlafaxine were prepared using ethyl cellulose (EC) as a wall forming hydrophobic polymer. Usually, it is difficult to control initial sudden release of highly water-soluble drugs. In this regard, double-layered microparticles were prepared not only...