Intestinal epithelial cell polarity defects in disease: lessons from microvillus inclusion disease

• Main Authors: Kerstin Schneeberger (Author), Sabrina Roth (Author), Edward E. S. Nieuwenhuis (Author), Sabine Middendorp (Author)
• Formato: Livro
• Publicado em: The Company of Biologists, 2018-02-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The intestinal epithelium is a highly organized tissue. The establishment of epithelial cell polarity, with distinct apical and basolateral plasma membrane domains, is pivotal for both barrier formation and for the uptake and vectorial transport of nutrients. The establishment of cell polarity requi...