PD‐L1 expression in megakaryocytes and its clinicopathological features in primary myelofibrosis patients

• Main Authors: Sze‐Hwei Lee (Author), Chien‐Chin Lin (Author), Chao‐Hong Wei (Author), Ko‐Ping Chang (Author), Chang‐Tsu Yuan (Author), Cheng‐Hong Tsai (Author), Jia‐Hao Liu (Author), Hsin‐An Hou (Author), Jih‐Lu Tang (Author), Wen‐Chien Chou (Author), Hwei‐Fang Tien (Author)
• Format: Book
• Published: Wiley, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Myeloproliferative neoplasms (MPNs) are characterized by upregulation of proinflammatory cytokines and immune dysregulation, which provide a reasonable basis for immunotherapy in patients. Megakaryocytes are crucial in the pathogenesis of primary myelofibrosis (PMF), the most clinically agg...