Successful delivery of docetaxel to rat brain using experimentally developed nanoliposome: a treatment strategy for brain tumor

• Main Authors: Tapan Kumar Shaw (Author), Dipika Mandal (Author), Goutam Dey (Author), Murari Mohan Pal (Author), Paramita Paul (Author), Samrat Chakraborty (Author), Kazi Asraf Ali (Author), Biswajit Mukherjee (Author), Amal Kumar Bandyopadhyay (Author), Mahitosh Mandal (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Docetaxel (DTX) is found to be very effective against glioma cell in vitro. However, in vivo passage of DTX through BBB is extremely difficult due to the physicochemical and pharmacological characteristics of the drug. No existing formulation is successful in this aspect. Hence, in this study, effor...