The delta opioid receptor agonist KNT‐127 relieves innate anxiety‐like behavior in mice by suppressing transmission from the prelimbic cortex to basolateral amygdala

• Main Authors: Ayako Kawaminami (Author), Daisuke Yamada (Author), Toshinori Yoshioka (Author), Azumi Hatakeyama (Author), Moeno Nishida (Author), Keita Kajino (Author), Tsuyoshi Saitoh (Author), Hiroshi Nagase (Author), Akiyoshi Saitoh (Author)
• Format: Book
• Published: Wiley, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Aim Excitatory projections from the prelimbic cortex (PL) to the basolateral nucleus of the amygdala (BLA) are implicated in the regulation of anxiety‐like behaviors, and we previously demonstrated that anxiolytic‐like effects of the selective delta‐opioid receptor (DOP) agonist KNT‐127 is...