Application of a validated HPLC-PDA method for the determination of melatonin content and its release from poly(lactic acid) nanoparticles
Melatonin is a natural hormone and with the advancement of age its production declines and thereby may result in some neurological disorders. Exogenous administration of melatonin has been suggested as a neuroprotective agent. Due to its low oral bioavailability, the loading of melatonin in polymeri...
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Elsevier,
2017-12-01T00:00:00Z.
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