Application of a validated HPLC-PDA method for the determination of melatonin content and its release from poly(lactic acid) nanoparticles

Melatonin is a natural hormone and with the advancement of age its production declines and thereby may result in some neurological disorders. Exogenous administration of melatonin has been suggested as a neuroprotective agent. Due to its low oral bioavailability, the loading of melatonin in polymeri...

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Glavni autori: Leiziani Gnatkowski Martins (Autor), Najeh Maissar khalil (Autor), Rubiana Mara Mainardes (Autor)
Format: Knjiga
Izdano: Elsevier, 2017-12-01T00:00:00Z.
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