Integrated Metabolomics and Network Pharmacology Revealed Hong-Hua-Xiao-Yao Tablet's Effect of Mediating Hormone Synthesis in the Treatment of Mammary Gland Hyperplasia

• Main Authors: Ziqing Gao (Author), Rui Mi (Author), Zhaoxi Cheng (Author), Xiaofeng Li (Author), Huawu Zeng (Author), Gaosong Wu (Author), Jing Zhao (Author), Weidong Zhang (Author), Ji Ye (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hong-Hua-Xiao-Yao Tablet (HHXYT) is a traditional Chinese medicine (TCM) formula that has been approved for the treatment of mammary gland hyperplasia (MGH), but its mechanism of action is unclear. In this study, a strategy that integrated metabolomics and network pharmacology was applied to systemi...