Hypothalamic hormone-sensitive lipase regulates appetite and energy homeostasis

• Main Authors: Cecilie Hundahl (Author), Petra Kotzbeck (Author), Hayley B. Burm (Author), Søren H. Christiansen (Author), Lola Torz (Author), Aske W. Helge (Author), Martin P. Madsen (Author), Cecilia Ratner (Author), Annette K. Serup (Author), Jonatan J. Thompson (Author), Thomas O. Eichmann (Author), Tune H. Pers (Author), David P.D. Woldbye (Author), Daniele Piomelli (Author), Bente Kiens (Author), Rudolf Zechner (Author), Louise J. Skov (Author), Birgitte Holst (Author)
• Format: Book
• Published: Elsevier, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The goal of this study was to investigate the importance of central hormone-sensitive lipase (HSL) expression in the regulation of food intake and body weight in mice to clarify whether intracellular lipolysis in the mammalian hypothalamus plays a role in regulating appetite. Methods: Usi...