PACAP38 synergizes with irradiation to suppress the proliferation of multiple cancer cells via regulating SOX6/Wnt/β-catenin signaling

• Main Authors: Ran Wu (Author), Chun-Xiang Cao (Author), Lu Cao (Author), Jun Su (Author), Ke-Man Liao (Author), Huan Li (Author), Qian Zhu (Author), Shu-Yan Li (Author), Min Li (Author), Jia-Yi Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundPituitary adenylate cyclase-activating polypeptide (PACAP) 38 is an endogenous neuropeptide with diverse functions, notably its critical role in inhibiting tumor proliferation. Radiotherapy is an important step in the standard treatment modality of many tumors. Combining radiotherapy with...