Effect of pH on weakly acidic and basic model drugs and determination of their ex vivo transdermal permeation routes

ABSTRACT The aim of the present study was to investigate the effect of donor pH on the transdermal permeability of the model drugs across rat skin and also to determine the major route of transport of the drugs. Weakly acidic drugs (partition coefficient) ibuprofen (3.6), aceclofenac (3.9), glipizid...

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Main Authors: Pranitha Akula (Author), Lakshmi P.K (Author)
Format: Book
Published: Universidade de São Paulo, 2018-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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