An Orally Bioavailable (Mice) Prodrug of Glutathione

• প্রধান লেখক: Daune L. Crankshaw (লেখক), Jacquie E. Briggs (লেখক), Robert Vince (লেখক), Herbert T. Nagasawa (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2021-06-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

L-Cysteine-glutathione mixed disulfide (CySSG), a prodrug of glutathione (GSH), was found to be orally bioavailable in mice, and protected mice against a toxic dose of acetaminophen. If oral bioavailability can also be demonstrated in humans, a wide range of applicability for CySSG can be envisioned...