Half-Sandwich Arene Ruthenium(II) Thiosemicarbazone Complexes: Evaluation of Anticancer Effect on Primary and Metastatic Ovarian Cancer Cell Lines

In this study, we describe the synthesis, characterization and antiproliferative activity of three organo-ruthenium(II) half-sandwich complexes [RuCl(η6-p-cym)(N,S-L)]Cl (I, II, and III). To form these complexes, three thiosemicarbazone ligands (TSCs) were synthesized; L = 5-nitro-2-carboxyaldehyde-...

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Main Authors: Seminay Guler (Author), Hulya Ayar Kayali (Author), Egemen Orkun Sadan (Author), Betul Sen (Author), Elif Subasi (Author)
Format: Book
Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
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