Interleukin-17 plays a role in dental pulp inflammation mediated by zoledronic acid: a mechanism unrelated to the Th17 immune response?

• Main Authors: Anna Clara Aragão Matos CARLOS (Author), José Vitor Mota LEMOS (Author), Marcela Maria Fontes BORGES (Author), Maria Carolina Portela ALBUQUERQUE (Author), Fabrício Bitu SOUSA (Author), Ana Paula Negreiros Nunes ALVES (Author), Thinali Sousa DANTAS (Author), Paulo Goberlânio de Barros SILVA (Author)
• Format: Book
• Published: University of São Paulo, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Objective To evaluate the influence of RORγT inhibition by digoxin on inflammatory changes related to interleukin-17 (IL-17) in the pulp of rats treated with zoledronate (ZOL). Methodology Forty male Wistar rats were divided into a negative control group (NCG) treated with saline solution,...