Epidermal growth factor effect on lipopolysaccharide-induced inflammation in fibroblasts derived from diabetic foot ulcer

• Main Authors: Yssel Mendoza-Marí (Author), Ariana García-Ojalvo (Author), Maday Fernández-Mayola (Author), Nadia Rodríguez-Rodríguez (Author), Indira Martinez-Jimenez (Author), Jorge Berlanga-Acosta (Author)
• Format: Book
• Published: SAGE Publishing, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background Diabetic foot ulcers (DFU) are characterised by high levels of inflammatory mediators, resulting from sustained hyperglycaemic insult and the local microbial biofilm. The intralesional administration of epidermal growth factor (EGF) has emerged as an effective treatment that stimulates gr...