Opioid-Induced Hyperalgesia in Chronic Pain Patients and the Mitigating Effects of Gabapentin

Opioid-Induced Hyperalgesia in Chronic Pain Patients and the Mitigating Effects of Gabapentin

Chronic pain patients receiving opioid drugs are at risk for opioid-induced hyperalgesia (OIH), wherein opioid pain medication leads to a paradoxical pain state. OIH involves central sensitization of primary and secondary afferent neurons in the dorsal horn and dorsal root ganglion, similar to neuro...

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Main Authors: Nicoleta eStoicea (Author), Daric eRussell (Author), Greg eWeidner (Author), Michael eDurda (Author), Nicholas Christopher Joseph (Author), Jeffrey eYu (Author), Sergio Daniel Bergese (Author)
Format: Book
Published: Frontiers Media S.A., 2015-05-01T00:00:00Z.
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