High-Salt Attenuates the Efficacy of Dapagliflozin in Tubular Protection by Impairing Fatty Acid Metabolism in Diabetic Kidney Disease

• मुख्य लेखकों: Meina Zou (लेखक), Yanrong Chen (लेखक), Zongji Zheng (लेखक), Shuyue Sheng (लेखक), Yijie Jia (लेखक), Xiangyu Wang (लेखक), Shijing Ren (लेखक), Yanling Yang (लेखक), Xiaomin Li (लेखक), Wenhui Dong (लेखक), Meiping Guan (लेखक), Qian Zhang (लेखक), Yaoming Xue (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

High-salt intake leads to kidney damage and even limits the effectiveness of drugs. However, it is unclear whether excessive intake of salt affects renal tubular energy metabolism and the efficacy of dapagliflozin on renal function in diabetic kidney disease (DKD). In this study, we enrolled 350 DKD...