Assessment of the dual role of Lyonia ovalifolia (Wall.) Drude in inhibiting AGEs and enhancing GLUT4 translocation through LC-ESI-QTOF-MS/MS determination and in silico studies

• Main Authors: Neha Sahu (Author), Nitesh Singh (Author), Kamal Ram Arya (Author), Sabbu Sathish Reddy (Author), Amit Kumar Rai (Author), Vijaya Shukla (Author), Jyotsana Pandey (Author), Tadigoppula Narender (Author), Akhilesh Kumar Tamrakar (Author), Brijesh Kumar (Author), Bikash Kumar Rajak (Author), Sumira Malik (Author), Sarvesh Rustagi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Diabetes mellitus (DM) is a metabolic disorder that results in glucose accumulation in the blood, accompanied by the production of advanced glycation end products (AGEs) through glycation of cellular proteins. These AGEs interfere with insulin signaling and prevent GLUT4 membrane trans...