Impact of study design and statistical model in pharmacogenetic studies with gene‐treatment interaction

Abstract Gene‐treatment interactions, just like drug‐drug interactions, can have dramatic effects on a patient response and therefore influence the clinician decision at the patient's bedside. Crossover designs, although they are known to decrease the number of subjects in drug‐interaction stud...

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Autores principales: Camille Couffignal (Autor), France Mentré (Autor), Julie Bertrand (Autor)
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Publicado: Wiley, 2021-04-01T00:00:00Z.
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Número de Clasificación: A1234.567
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