Grape seed proanthocyanidin extract targets p66Shc to regulate mitochondrial biogenesis and dynamics in diabetic kidney disease

Mitochondrial biogenesis and dynamics are associated with renal mitochondrial dysfunction and the pathophysiological development of diabetic kidney disease (DKD). Decreased p66Shc expression prevents DKD progression by significantly regulating mitochondrial function. Grape seed proanthocyanidin extr...

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Main Authors: Yiyun Song (Author), Hui Yu (Author), Qiaoling Sun (Author), Fei Pei (Author), Qing Xia (Author), Zhaoli Gao (Author), Xianhua Li (Author)
Format: Book
Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
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