Gastric Cancer Mesenchymal Stem Cells Inhibit NK Cell Function through mTOR Signalling to Promote Tumour Growth

• Main Authors: Shuwei Guo (Author), Chao Huang (Author), Fengfeng Han (Author), Bin Chen (Author), Ying Ding (Author), Yuanyuan Zhao (Author), Zhihong Chen (Author), Shaodi Wen (Author), Mei Wang (Author), Bo Shen (Author), Wei Zhu (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The dysfunction of natural killer (NK) cells has been increasingly reported in malignancies, especially in solid tumours. Mesenchymal stem cells (MSCs) exhibit pleiotropic functions that include mediating immune cell exhaustion which is implicated in cancer progression. However, the association of M...