Gastric Cancer Mesenchymal Stem Cells Inhibit NK Cell Function through mTOR Signalling to Promote Tumour Growth

• Hauptverfasser: Shuwei Guo (Verfasst von), Chao Huang (Verfasst von), Fengfeng Han (Verfasst von), Bin Chen (Verfasst von), Ying Ding (Verfasst von), Yuanyuan Zhao (Verfasst von), Zhihong Chen (Verfasst von), Shaodi Wen (Verfasst von), Mei Wang (Verfasst von), Bo Shen (Verfasst von), Wei Zhu (Verfasst von)
• Format: Buch
• Veröffentlicht: Hindawi Limited, 2021-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

The dysfunction of natural killer (NK) cells has been increasingly reported in malignancies, especially in solid tumours. Mesenchymal stem cells (MSCs) exhibit pleiotropic functions that include mediating immune cell exhaustion which is implicated in cancer progression. However, the association of M...