Antioxidant Properties of Zinc and Copper-Blood Zinc-to Copper-Ratio as a Marker of Cancer Risk BRCA1 Mutation Carriers

• Main Authors: Milena Matuszczak (Author), Adam Kiljańczyk (Author), Wojciech Marciniak (Author), Róża Derkacz (Author), Klaudia Stempa (Author), Piotr Baszuk (Author), Marta Bryśkiewicz (Author), Cezary Cybulski (Author), Tadeusz Dębniak (Author), Jacek Gronwald (Author), Tomasz Huzarski (Author), Marcin Lener (Author), Anna Jakubowska (Author), Marek Szwiec (Author), Małgorzata Stawicka-Niełacna (Author), Dariusz Godlewski (Author), Artur Prusaczyk (Author), Andrzej Jasiewicz (Author), Tomasz Kluz (Author), Joanna Tomiczek-Szwiec (Author), Ewa Kilar-Kobierzycka (Author), Monika Siołek (Author), Rafał Wiśniowski (Author), Renata Posmyk (Author), Joanna Jarkiewicz-Tretyn (Author), Rodney Scott (Author), Jan Lubiński (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pathogenic mutations in BRCA1 (BReast CAncer gene 1) confer high risks of both breast (up to 70%) and ovarian (up to 40%) cancers. Zinc (Zn) and copper (Cu) are essential for various physiological functions, including antioxidant reactions. Their balance, reflected in the Zn/Cu ratio, plays a crucia...