Benzimidazole-based derivatives as privileged scaffold developed for the treatment of the RSV infection: a computational study exploring the potency and cytotoxicity profiles

• Main Authors: Elena Cichero (Author), Michele Tonelli (Author), Federica Novelli (Author), Bruno Tasso (Author), Ilenia Delogu (Author), Roberta Loddo (Author), Olga Bruno (Author), Paola Fossa (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Respiratory syncytial virus (RSV) has been identified as a main cause of hospitalisation in infants and children. To date, the current therapeutic arsenal is limited to ribavirin and palivizumab with variable efficacy. In this work, starting from a number of in-house series of previously described a...