AST-120 alleviates renal ischemia-reperfusion injury by inhibiting HK2-mediated glycolysis

• Main Authors: Jinmeng Zhou (Author), Jinbao Zhang (Author), Feng Xu (Author), Haijin Gao (Author), Lei Wang (Author), Yutong Zhao (Author), Ke Li (Author)
• Format: Book
• Published: BMC, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Objective Renal ischemia/reperfusion injury (IRI) is a major cause of acute kidney injury (AKI), which is associated with high incidence and mortality. AST-120 is an oral carbonaceous adsorbent that can alleviate kidney damage. This study aimed to explore the effects of AST-120 on renal IRI...