Schistosomicidal effects of histone acetyltransferase inhibitors against Schistosoma japonicum juveniles and adult worms in vitro.

• Main Authors: Jing Xu (Author), Jing-Yi Wang (Author), Ping Huang (Author), Zi-Hao Liu (Author), Yu-Xin Wang (Author), Run-Ze Zhang (Author), Hui-Min Ma (Author), Bi-Yue Zhou (Author), Xiao-Yan Ni (Author), Chun-Rong Xiong (Author), Chao-Ming Xia (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Schistosomiasis is a relatively neglected parasitic disease that afflicts more than 250 million people worldwide, for which the control strategy relies mainly on mass treatment with the only available drug, praziquantel (PZQ). This approach is not sustainable and is a...