Pharmacokinetic assessment of tacrolimus in combination with deoxyschizandrin in rats

• Main Authors: Jianguo Sun (Author), Zhipeng Wang (Author), Na Liu (Author), Zhijun Liu (Author), Lili Cui (Author), Xia Tao (Author), Wansheng Chen (Author), Shouhong Gao (Author), Zhijun Wu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundTacrolimus (Tac) is commonly used for postoperative immunosuppressive therapy in transplant patients. However, problems, for example, low bioavailability and unstable plasma concentration, persist for a long time, Studies have reported that the deoxyschizandrin could effectively improve th...